STUDIES ON THE MECHANISM OF EXPERIMENTAL PROTEINURIA
نویسندگان
چکیده
منابع مشابه
Studies on the Mechanism of Experimental Proteinuria
When renin is administered intramuscularly to the rat, massive proteinuria occurs without a significant elevation of mean arterial blood pressure. The intravenous administration of renin to normal rats results in a great increase in urinary protein excretion. This response to renin is abolished by bilateral adrenalectomy. While the adrenalectomized rat fails to respond to intravenous renin with...
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Renin-induced proteinuria in the rat was investigated, with special emphasis on the relationship between the enzymatic activity and the proteinuric effect of renin. The dependence of the proteinuric effect on the enzymatic activity was shown by using (a) renin preparations of widely varying purity and (b) chemically modified "active" and "inactive" renin derivatives. Angiotensin II, the pressor...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1952
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.96.6.643